ACI (CARTICEL) PROCEDURE (FEMORAL CONDYLE ONLY)

Autologous Chondrocyte Implantation (Femoral Condyle Only)
Autologous Chondrocyte Implantation
(Femoral Condyle Only)
Rehabilitation Guideline
- THE FOLLOWING PROTOCOL HAS BEEN ESTABLISHED AS A REFERENCE FOR REHABILITATION FOLLOWING AUTOLOGOUS CHONDROCYTE IMPLANTATION OF THE FEMORAL CONDYLE. THIS IS TO SERVE ONLY AS A GUIDELINE. INDIVIDUAL CASES WILL VARY. THE EMPHASIS OF THIS PROTOCOL IS
TO PRESERVE THE STABILITY OF THE SURGICAL PROCEDURE AND RETURN THE PATIENT TO AN OPTIMAL LEVEL OF FUNCTION.
- ALTHOUGH TIME FRAMES HAVE BEEN ESTABLISHED, IT IS MORE IMPORTANT THAT GOALS ARE REACHED AT THE END OF EACH PHASE PRIOR TO PROGRESSION TO THE NEXT.
- IT IS IMPORTANT TO AVOID EXCESSIVE LOADING/WEIGHTBEARING THROUGH THE GRAFT SITE TO ENSURE PROPER HEALING. TAKE NOTE OF SPECIFIC PRECAUTIONS MENTIONED IN THE PROTOCOL. INFORMATION REGARDING THE LOCATION OF THE IMPLANTATION SITE SHOULD BE OBTAINED
FROM THE SURGEON.
- PAIN AND SWELLING NEED TO BE CAREFULLY MONITORED THROUGHOUT THE REHABILITATION PROCESS. IF EITHER OCCUR, THE CAUSATIVE ACTIVITY NEEDS TO BE IDENTIFIED AND APPROPRIATELY ADJUSTED TO LESSEN THE IRRITATION. IGNORING THESE SYMPTOMS MAY COMPROMISE THE
SUCCESS OF THE SURGERY AND THE PATIENT'S OUTCOME.
EARLY PHASE - DAY 1 TO WEEK 12
Weight bearing
Weeks 0 - 2
- Non weight bearing for 2 weeks
- Hinge brace locked at 0o. Unlock for CPM and exercise only
Weeks 2 - 4
- Partial weight bearing (30 - 40 lbs.) with bilateral crutches (If the patient is extremely small or large, this may vary.)
- Important to avoid twisting/pivoting on involved knee while weight bearing.
- Slowly open brace 20o at a time as patient gains quadriceps control
- Discard brace when quadriceps are strong enough to control the leg in a straight leg raise (SLR) without extensive lag and involved leg shows stability with partial weight bearing
- Consider aquatic therapy for gait training utilizing water's buoyancy factor to limit weight bearing. Incision will need to be healed
Weeks 4 - 6
- Continue PWB status. May progress to one crutch if gait pattern is normal and pain free with 2 crutches with incremental progression of weight bearing
- Important to avoid twisting/pivoting on implanted knee
Weeks 6 - 12
- Progress to full weight bearing (FWB) and discard crutches if pain free with minimal edema. Gait pattern should be normal
Range of Motion
CPM
- Begin 6 - 24 hours after surgery
- Use in 2 hour increments for 8 - 10 hours/day
- May use CPM for up to 6 weeks. Important to use it for the first 4 weeks
- Start with settings of 0 - 40/45o, increase 5 - 10o per day per patient comfort and edema
ROM Exercise
- Active, active-assisted, and passive ROM techniques
- Patella mobilization - start early 1-2 weeks post op
- Hamstring, gastroc/soleus, quadriceps and hip stretching
- After week 2 may use stationary cycle for ROM only (very light resistance) with involved leg if 90o has been attained
- Goal: 0-90o by 4 weeks, 110o by 5 weeks, 130o by 6 weeks post op.
Edema Control
- Ice, elevation, edema modalities and edema massage as needed (no non-steroidal anti inflammatory medication)
Strengthening
Weeks 1 - 2
- Isometrics-quad sets, straight leg raises and hamstring isometrics, straight leg raises in four directions (hip flexion, extension, abduction, adduction). Do exercises in the brace if quadriceps control is inadequate. Can add resistance above the
knee
- Consider use of biofeedback or electrical stimulation for muscle reeducation
- Isometrics in varied knee positions-pain free
Weeks 2 - 6
- Progress QS, SLR, hip strengthening as tolerated, can add resistance below the knee if quad control adequate
- Begin progressive closed chain exercise starting with light resistance, i.e. supine leg press with Theraband, sled or shuttle and staying within weight bearing restriction
- Consider Carticel graft site with closed chain activities:
- If anterior - avoid loading in full extension
- If posterior - avoid loading in flexion >45o
- Consider aquatic therapy strengthening and conditioning
Weeks 6-10
- Weight shifting activities if FWB
- Progress bilateral closed chain strengthening in FWB if appropriate, i.e. add shallow squats and shuttle
- Open chained knee strengthening - consider machine weights, manual, isokinetic, concentric and eccentric resistance
Weeks 10-12
- Isometrics with foot in fixed position at multiple angles, avoid position that would put stress on chondrocyte implantation
- Progress bilateral closed chain exercises in pain free range using resistance less than person's body weight
- Progress to standing squats (0-45o) with correct positioning; avoid anterior tibial/knee movement to lessen sheer forces on the knee joint
- Continue quadriceps and hamstring strengthening (PRE's/machines, manual resistive exercises concentric and eccentric, stool scouts, isokinetic strengthening, etc.)
- Progressive resistive exercises (PRE's) for gastroc/soleus, hips and upper quadrant
- Consider multi-hip for involved side unilateral weight bearing/balance/stabilization training
Cardiovascular/Walking Activities
- Choose at least one activity for 25 - 40 minutes, 3 times/week: cycle with uninvolved extremity; swimming with straight leg kick only; upper body ergometer
- Treadmill: Weeks 7-8 if FWB, forward and backward walking at slower pace. Emphasis on proper gait pattern
- Weeks 8-12: stationary bike; stair master in limited arcs of motion; treadmill with incline 2-3o to reduce loads, may progress speeds; rower with shortened arcs of motion
Functional/Balance Activities
- Weeks 8-12: balance training on involved leg - eyes open, eyes closed if motor control adequate; consider balance/tilt board, Baps, ball throws, etc.
Goals to be met at the end of Early Phase
- Full ROM
- Minimal/slight edema level
- Pain free tolerance to Early Phase exercise with adequate stability, motor control
- Minimal occasional pain only
TRANSITIONAL PHASE - WEEK 13 THROUGH MONTH 6
Range of Motion
- Maintain full active/passive ROM, patella mobility and surrounding muscular flexibility (quads, hamstrings, gastroc/soleus, abductors and adductors)
Strengthening
- Advance bilateral and unilateral closed chain exercise (consider step-ups (low step), emphasize concentric/eccentric control)
Cardiovascular/Walking Activities
- Continue cardiovascular training (Stair master, biking, swimming)
- Treadmill may progress to faster speeds to achieve mild impact tolerance
Balance/Functional Training
- Progress balance/proprioceptive training (i.e., ball throws or T Band resistance in unilateral stance, etc.)
- Consider slide board
- Consider sport cord lateral drills
- Continue to avoid twisting/pivoting on implanted knee
Goals to be met at the end of Transitional Phase
- Minimal pain ROM
- >80% quadriceps and hamstring strength
- Minimal pain free status with Transitional Phase exercise, no edema
MID PHASE - MONTH 7 THROUGH MONTH 9
Strengthening
- Advance strength training - increase resistance and decrease reps, emphasize single leg loading
- Increase work loads to knees in sagittal plane of motion (bending/straightening) using a variety of exercises
Cardiovascular Training
- Continue per Transitional Phase endurance training
- Emphasize sport specific conditioning if within activity guidelines - see below
Functional/Balance Training
- Initiate light plyometric activity at 9 months (vertical, horizontal jumping, bilateral lateral jumping etc.); emphasis on eccentric control with landing. Progress as tolerated and per motor control to diagonal and unilateral plyometric training
Walking/Weightbearing
- Utilize pain/swelling as guideline; if either occur, reduce impact activities
- Treadmill on an incline - may progress to faster speeds to achieve mild "impact" without running.
FINAL PHASE - MONTH 10 THROUGH MONTH 18
Walking/Weightbearing
- Initiate impact training
- Initiate light jog on treadmill utilizing slight incline; start with 2 minute walk, 2 minute jog, etc.
Strengthening
- Advance training with heavier weights and fewer repetitions to increase size/mass of muscles
- Emphasize single leg loading and loading in full weight bearing
Function/Cardiovascular Training
- A progressive running and agility program should be incorporated beginning with straight plane running with increasing speeds
- Cutting drills should begin with slow "S" cutting with progressive speeds; if stable, sharper "V" cutting may be incorporated with sport specific drills
- High impact activities (basketball, tennis, etc.) may begin at 16 months if pain free
- Return to sports may vary according to individual MD guidelines
TIMELINE FOR ACTIVITIES
- Low Impact Activities: 9-12 Months
Skating, Roller Blading, Cross Country Skiing, Cycling
- Repetitive Impact Activities: 13-15 Months
Jogging, Running, Aerobic Classes
- High Level Activities: 16-18 Months
Tennis, Basketball

For specific questions on the rehab protocols, please contact Lisa Giannone, P.T.
San Francisco, California
Phone: 415-387-6564
Fax: 415-387-2013

THIS MATERIAL DOES NOT CONSTITUTE MEDICAL ADVICE. IT IS INTENDED FOR INFORMATIONAL PURPOSES ONLY. PLEASE CONSULT A PHYSICIAN OR PHYSICAL THERAPIST FOR SPECIFIC TREATMENT RECOMMENDATIONS.
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